Магнітні рідини на основі магнетиту і доксорубіцину для спрямованої доставки лікарського засобу

A. L. Petranovska; N. V. Abramov; S. P. Turanska; P. P. Gorbyk; A. P. Kusyak

doi:10.15407/hftp06.03.343

Authors

A. L. Petranovska Chuiko Institute of Surface Chemistry of National Academy of Sciences of Ukraine
N. V. Abramov Chuiko Institute of Surface Chemistry of National Academy of Sciences of Ukraine
S. P. Turanska Chuiko Institute of Surface Chemistry of National Academy of Sciences of Ukraine
P. P. Gorbyk Chuiko Institute of Surface Chemistry of National Academy of Sciences of Ukraine
A. P. Kusyak Zhytomyr Ivan Franko State University

DOI:

https://doi.org/10.15407/hftp06.03.343

Keywords:

magnetic liquid, modification, biocompatible coatings, hydroxyapatite, adsorption, doxorubicin

Abstract

Technological methods for synthesis of new magnetic liquids based on modified magnetite colloidal systems containing chemotherapeutic agent doxorubicin are developed. The magnetite surface modifying was carried out with hydroxyapatite, the magnetic liquid was stabilized with sodium oleate and polyethylene glycol to give biocompatible properties and low ability to adsorb plasma proteins. Physico-chemical properties of developed colloid systems have been studied.

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