Application of Ion-Forming Additive to Mass Spectrometric Analysis and Identification of Biological Objects

Authors

  • O. V. Severinovskaya Chuiko Institute of Surface Chemistry of National Academy of Sciences of Ukraine
  • O. A. Varzatskiy Vernadsky Institute of general and inorganic chemistry of National Academy of Sciences of Ukraine
  • S. V. Shulga Vernadsky Institute of general and inorganic chemistry of National Academy of Sciences of Ukraine
  • V. A. Pokrovskiy Chuiko Institute of Surface Chemistry of National Academy of Sciences of Ukraine
  • T. Yu. Gromovoy Chuiko Institute of Surface Chemistry of National Academy of Sciences of Ukraine

Abstract

Application of bis-trifluorsulphonimide as ion-forming additive to study of proteins (lisozyme and insulin) by matrix-assisted laser desorption/ionization technique was investigated. It has been shown that in the case of lisozyme interaction occurs with anions while in the case of insulin - with cations of ion-forming additive. It has been concluded that interaction between proteins and ion-forming additive has a specific character. Thus, the technique may be proposed as alternative approach to biomolecules investigations.

References

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How to Cite

(1)
Severinovskaya, O. V.; Varzatskiy, O. A.; Shulga, S. V.; Pokrovskiy, V. A.; Gromovoy, T. Y. Application of Ion-Forming Additive to Mass Spectrometric Analysis and Identification of Biological Objects. Him. Fiz. Tehnol. Poverhni 2011, 2, 366-369.

Issue

Vol. 2 No. 3 (2011): Chemistry, Physics and Technology of Surface / Himia, Fizika ta Tehnologia Poverhni

Section

Articles

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